Laxatives becomes the most frequent medication for constipation, it works as an stimulant for softening intestines and increasing stool’s hydration. Laxatives are the one of the most commonly bought over the counter for constipation, incomplete evacuation, passage of hard stools, unsatisfactory and infrequent stool passage.
The Global laxatives market is expected to grow at a CAGR of 6.9% and expended to reach US$8.71Bn by 2025.About 24% to 50% laxatives prevalence in older adults has been reported in western countries. In the U.S. annually laxatives prescription are accounted for 2.5 million visits for constipation and about 20,000 are hospitalized.
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Initial treatment for constipation includes Osmotic laxatives such as polyethylene glycol or lactulose are used in patients having symptom of neglecting fiber. Emollient laxatives soften stool by hydrating and allowing intestinal fluids to reducing fecal mass. Stimulant laxatives are used for patients not responding osmotic laxatives. Fiber is the most common laxative recommended by doctors for constipation, however lubricant laxatives are best for curing initial constipation, these laxatives can interface with body’s absorption of tat soluble vitamins.
The geographical distribution of the global laxatives market considered the regional markets such as North America, Europe, Asia Pacific, Middle East and North Africa and rest of the world.
In regional segmentation North America accounted the largest market share of laxatives market followed with Europe and Asia-Pacific respectively. However the majority of sales of laxatives will come from the U.S. which represents approximately 86% of the market by the end of the forecast period. In the U.S. laxatives are commonly prescribed class of medication for chronic pain; almost 50% of the U.S. population has suffering from on or other type of constipation.
Persistent constipation may lead to serious medical squeal including bowel obstruction and fecal impaction; increase in number of oral medications that are specifically designed to elevated use of prescribed drugs and medical services will grow the laxatives market. The leading players of laxatives market are Bayer AG, Abbott laboratories, Sucampo, Glaxo Smith, Astrazeneca Plc, and many others.
Increasing emphasis has been placed on demonstrating new therapeutic treatment for curing constipation. Laxatives are effective in bowel movements and difficult stool passage; nearly 14% of the general population loose stools are rarely present without use of laxatives. Constipation is more common in women and older adults, they deal with ongoing constipation as slow down of digestive function. However elderly patients with normal bowel frequency regard themselves as being constipated and take laxatives.
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Laxatives are effective, but excessive use of laxatives can lead to an electrolyte imbalance, lower the natural digestive process and affect the blood flow hormones. Constipation is a heterogeneous motility disorder associated with different patients with different reasons like lack of fiber, dehydration, stress, lack of sleep and irregular diet and routine, abdominal bloating and infrequent bowel movements. About 81% of the patients were somehow pleased with bowel frequency, 41% are cited for abdominal pain and 21% for incontinence. Lifestyles improvements may improve constipation and reduces the use of laxatives.