Global market for cystic fibrosis therapeutics is projected to grow at a compound annual growth rate (CAGR) of 10% during the forecast period of 2022 to 2030. Cystic fibrosis is a genetic condition that mostly impacts the lungs but can also impact other organs and systems in the body such as the pancreas, liver, and kidneys. of chloride. Several methods, including inhalation and oral administration, are available for delivering these medications to the patient.
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In addition, an increase in the global prevalence of cystic fibrosis and an increase in the level of awareness about cystic fibrosis both contribute to an upward trend in the cystic fibrosis market. For instance, the Cystic Fibrosis Foundation Patient Registry reports that there are more than 30,000 people living with cystic fibrosis in the United States, and more than 70,000 people living with the disease globally. In addition, around one thousand new instances of CF are identified each year, and the age at which a diagnosis is made for more than seventy-five percent of people who have CF is two. The expansion of the cystic fibrosis treatments market is also driven by the increasing amount of money that the government invests in research and development within the healthcare industry. The development of generic medications and the relatively high cost of treating cystic fibrosis are both factors that work against the expansion of the market.
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Developing countries, such as those in the Asia-Pacific area, have a lower level of awareness when it comes to reading the cystic fibrosis diagnosis of neonates. In addition, newborns in a number of countries are not screened for cystic fibrosis (CF) at the time of birth, and national registries sometimes lack data, both of which hinder the expansion of the cystic fibrosis market. On the other hand, the launch of numerous new drugs that have improved productivity and the growth of healthcare R&D facilities are anticipated to provide profitable prospects in the market for cystic fibrosis therapies. In addition, the expansion of the healthcare sector and the rise in the number of research and development activities carried out by key players are anticipated to drive the growth of the market during the course of the forecast period. In addition, the growing incidence of cystic fibrosis has resulted in an increased demand for novel and cutting-edge therapeutic approaches to the disease’s management. As a result, this has led to an increase in the number of pharmaceuticals that are currently in the pipeline in the market, which is anticipated to give lucrative chances for the expansion of the market over the course of the projection period.
On the basis of the drug class, the market is segmented as follows: bronchodilators, mucolytics, cystic fibrosis transmembrane conductance regulator (CFTR), and pancreatic enzyme supplements, and others. CFTR remains as the market that holds a dominant position. This segment tops the market as it speeds up the normally sluggish process of the body’s function at the cellular level, which it also improves, as well as the function of the CFTR protein. In addition, cutting-edge therapies that involve the use of triple medication combinations are expected to be major drivers of market growth during the forecast period.
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Because of the rise in the consumption of oral medications around the world, the oral route of administration currently (2021) holds the largest market share in comparison to parenteral route of administration. As a result of the development of novel drug formulations, effective therapy can now be obtained using methods that do not involve the need for intrusive procedures and can be easily taken. In addition, it is anticipated that the parenteral drug segment will record a compound annual growth rate (CAGR) that is relatively higher during the forecast period. In addition, there has been an increase in the use of injections as a treatment for CF, which has led the major companies in the industry to concentrate on the mass manufacture of sophisticated formulation injections.
Retail pharmacies & drug stores, online pharmacies, and hospital pharmacies make up the market. Retail pharmacies and drugstores dominate the market. Retail pharmacies and drug shops are expected to dominate the sector during the forecast period, over internet pharmacies and hospital pharmacies. Online pharmacies are expected to grow the fastest during the projection period. The growth of online pharmacies is projected to be fuelled by an increase in patients who value the ease of receiving their drugs, as well as other considerations.
In 2021, North America held the largest market for cystic fibrosis treatments and drugs. The dominance of the market in this region is due to a growth in cystic fibrosis (CF) diagnoses, respiratory illnesses that affect CF, R&D activities, healthcare spending, and other factors. Europe will maintain a second-place position after North America, researchers predict. Rising disposable income, increasing prevalence, more modern treatments to enhance patient outcomes, etc. In Asia-Pacific, expansion opportunities are expected. Increased senior population, healthcare facilities, public awareness of therapy, and other causes. Latin America, the Middle East, and Africa are “rest of the planet” regions. Unmet healthcare demands, low prevalence of the illness, inadequate awareness of healthcare facilities, and others are expected to slow expansion in these locations.
Vertex is the sole company with CFTR modulator medications, while others have additional drugs on the market. Chiesi has two inhaled antibiotics: Bramitob/Bethkis (tobramycin) in the US and 5EU (France, Germany, Italy, Spain, and the UK) and Quinsair (levofloxacin) in the 5EU. TOBI (tobramycin) and TOBI Podhaler (tobramycin inhalation powder) are popular inhaled antibiotics. Viatris (formerly Mylan) owns the most common inhaled antibiotics, while Nestlé HealthScience has two PERT medicines. PERT’s Zenpep (pancrelipase) and Viokace (pancrelipase). Gilead, Teva, Genentech, AbbVie, Vivus, Horizon Therapeutics, and Pharmaxis also make cystic fibrosis drugs.
Key Market Trends
- Global market for cystic fibrosis therapeutics is projected to grow at a compound annual growth rate (CAGR) of 10% during the forecast period of 2022 to 2030.
- CFTR remains as the market that holds a dominant position.
- oral route of administration currently holds the largest market share in comparison to parenteral route of administration.
- Retail pharmacies and drugstores dominate the market.
- In 2021, North America held the largest market for cystic fibrosis treatments and drugs.
- Europe will maintain a second-place position after North America.
- Vertex is the sole company with CFTR modulator medications, while others have additional drugs on the market.
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